Renal Ischemia Reperfusion Causes Brain Hippocampus Oxidative Damage and Inhibition Effect
نویسندگان
چکیده
BACKGROUND The acute kidney injury (AKI) may do damage to remote organs. Objective of the study is to investigate effect of seaweed extract (SE) on brain oxidative damage in kidney ischemia/reperfusion rats. MATERIAL AND METHODS Animals were randomly divided into five groups. SE pre-fed to rats. RESULTS Kidney I/R may cause oxidative injury in kidneys and brains tissue in rats. SE pre-treatment can decrease lipid peroxidation levels and increase antioxidant enzymes activities in kidney and brain hippocampus of kidney I/R rats. CONCLUSION Our results indicate that SE is useful for brain nerve function keeping in kidney I/R rats.
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